Non-oral estradiol (a specific form of estrogen) at the lowest dose and for the shortest period of time was associated with the lowest risk of developing high blood pressure.Įmbargoed until 4 a.m. Oral estrogen was associated with a 14% higher risk of high blood pressure compared to transdermal estrogen creams and a 19% greater risk of high blood pressure compared to vaginal estrogen creams or suppositories.A study of more than 100,000 women, ages 45 and older, taking oral estrogen hormone therapy for menopause, has found that estrogen ingested in pill form may be associated with an increased risk of high blood pressure compared to transdermal and vaginal estrogen.
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